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Science & research

The scientific foundation of our developments

A technology studied for more than 20 years at leading Ukrainian scientific institutions underpins our programmes in oncology and gerontology.

Scientific approach

A research programme built on the substance

The Institute's work is built on a biologically active substance whose synthesis technology was developed in the 1990s. It has been studied for more than 20 years at leading research and clinical institutions in Ukraine.

The substance has broad potential for application. The Institute currently works in two main directions: oncology and gerontology.

Research directions

Oncology and gerontology

Abstract visual: tumour cells attempt to divide and break apart, while healthy cells remain intact
Primary direction

Oncology

A new class of selective cytostatic drugs: mechanism of action, preclinical research and clinical programme.

Oncology research
Abstract visual: a damaged section of the DNA double helix is restored
Second direction

Gerontology

A cellular detoxification technology for healthy longevity and quality of life.

Gerontology research
Development stages

From substance synthesis to clinical use

  1. 01

    Development

    The substance's synthesis technology and the creation of dosage forms.

  2. 02

    In vitro

    Study of the mechanism of action and selectivity in cell cultures.

  3. 03

    In vivo

    Antitumour activity in standard preclinical models.

  4. 04

    Clinical trials

    Development of clinical programmes across different tumour sites.

  5. 05

    Registration

    Registration and market introduction of the Institute's new developments.

  6. 06

    Clinical practice

    Use in clinics within individual protocols.

Scientific institutions

Where the technology was studied

The technology has been studied for more than 20 years at leading research institutions in Ukraine. Details of the nature and period of each study are provided after an NDA has been signed.
  1. 01R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of UkraineOncology and experimental pathologyKyiv
  2. 02SI "Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine"Pharmacology and toxicologyKyiv
  3. 03SI "D. F. Chebotarev Institute of Gerontology of the National Academy of Medical Sciences of Ukraine"GerontologyKyiv
  4. 04SI "Romodanov Neurosurgery Institute of the National Academy of Medical Sciences of Ukraine"Neurosurgery and neuro-oncologyKyiv
  5. 05SI "L. V. Gromashevsky Institute of Epidemiology and Infectious Diseases of the National Academy of Medical Sciences of Ukraine"Epidemiology and infectious diseasesKyiv
Documentation

Research materials

Research materials are provided to partners once the terms of cooperation have been agreed and an NDA has been signed.

  • Preclinical research

    Reports on in vitro and in vivo studies in both directions.

    After an NDA

  • Clinical trials

    Materials from Phase I–III clinical trials.

    After an NDA

  • Patents and registrations

    Intellectual property and regulatory documents.

    After an NDA

Development priorities

  • 01

    Expanding the clinical programme

    Extending clinical trials to new tumour sites.

  • 02

    Registration

    Registration and market introduction of the Institute's new developments.

  • 03

    Individual programmes

    Individual protocols informed by laboratory assessment of the patient's tumour.

  • 04

    Active longevity

    Developing the gerontology technology on the basis of completed preclinical research.